Applied Principles and Techniques of Depth Flow Filtration (DFF) and Tangential Flow Filtration (TFF) for BioPharm Downstream Purification hosted by BTEC
Date and Time
Tuesday Oct 25, 2022 Friday Oct 28, 2022
Location
All courses are offered on site at BTEC, other than online courses. The Golden LEAF BTEC building is located at 850 Oval Drive on NC State University's Centennial Campus.
Fees/Admission
Website
Description
Through participation in this four-day comprehensive filtration course, you will learn the fundamental principles and optimum applied techniques for depth filtration (DFF) and tangential flow filtration (TFF) used today in biopharmaceutical downstream purification.
The one-day lecture is designed to help individuals gain a solid understanding of the parameters and factors that affect DFF and TFF membrane performance and product recovery for both upstream cell clarification and downstream UF/DF biopharmaceutical applications. Depth filtration (DFF) will cover polymeric membrane and matrix media technologies, and tangential flow filtration (TFF) will cover both flat sheet cassette and hollow fiber element configurations. New advancements will be covered.
During the three-day hands-on laboratory workshop, DFF and TFF application trials are performed using state-of-the-art benchtop systems. Two full-day sessions are dedicated to cell clarification—with DFF on day one and by TFF on day two. Day three focuses on UF/DF by TFF. Data developed during these trials will be summarized, discussed, and applied to real scale-up system problems and SOP. The principles and techniques presented in the prerequisite lecture course will be applied in this workshop, which is limited to 12 participants.
